Temozolomide - Wikipedia
The active substance in Temodal, temozolomide, belongs to a group of anticancer medicines called alkylating agents. In the body, temozolomide is converted to another compound called MTIC. MTIC binds to the DNA of cells while they are reproducing, which stops cell division.
Temozolomide - Manfaat, Dosis, dan Efek Samping - Alodokter
Temozolomide is an alkylating agent that is used with radiation therapy to treat certain types of brain tumor in adults. It can cause serious side effects and interact with other drugs. Learn how to use, store, and dispose of temozolomide, and what precautions to take before taking it.
Temozolomide: Kegunaan, Dosis, Efek Samping - Hello Sehat
Temozolomide can have both beneficial and detrimental effects on immunotherapy efficacy by 1) reducing tumor burden by directly killing GBM, 2) increasing mutagenesis in surviving tumor cells and 3) resetting immune response by eliminating both suppressive and activated immune cells throughout the body.
Temozolomide - NCI - National Cancer Institute
Temozolomide is a medication used to treat certain types of brain tumors by slowing or stopping their growth. It belongs to a class of drugs called alkylating agents. Learn how to use it, what precautions to follow, what side effects to watch out for, and what special dietary instructions to follow.
Temozolomide (Temodal) | Cancer information | Cancer Research UK
Temozolomide is a drug approved to treat anaplastic astrocytoma and glioblastoma multiforme in adults. It is also being studied for other types of cancer and can be found in clinical trials.
Temozolomide: MedlinePlus Drug Information
Temozolomide (TMZ) is the first-choice chemotherapeutic agent in GBM; however, the development of resistance to TMZ often becomes the limiting factor in effective treatment. While O6-methylguanine-DNA methyltransferase repair activity and uniquely resistant populations of glioma stem cells are the most well-known contributors to TMZ resistance ...
Temozolomide Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
Temozolomide. Glioblastoma multiforme is the most common aggressive adult primary tumour of the central nervous system. Treatment includes surgery, radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. TMZ is an alkylating agent prodrug, delivering a methyl group to purine bases of DNA (O6-guanine; N7-guanin ….
Temozolomide: Uses, Interactions, Mechanism of Action - DrugBank Online
Temozolomide (TMZ) is a small alkylating molecule that introduces methyl groups into DNA. It is an analog of dacarbazine with an antineoplastic activity that was developed by Professor Malcolm Stevens in a multidisciplinary drug discovery laboratory in the pharmacy department at Aston University (UK) at the end of the 1980s.
Temozolomide (Oral Route) Description and Brand Names - Mayo Clinic
Temozolomide often causes nausea and vomiting. However, it is very important that you continue to take the medicine, even if you begin to feel ill. You may take the medicine on an empty stomach or at bedtime may help to lessen the nausea.
Temozolomide (Temodar): Uses & Side Effects - Cleveland Clinic
Temozolomide adalah obat kemoterapi untuk mengobati kanker otak, glioma, leukemia, dan kondisi lainnya. Dosis, aturan pakai, dan efek samping dari temozolomide dapat dilihat di ulasan ini. Temozolomide memiliki toksisitas yang bisa menyebabkan efek samping seperti mual, muntah, dan kesulit.